Bone marrow is an important tissue in the body that produces blood cells (red blood cells, white blood cells, platelets, etc.) and is found primarily in bone. Bone marrow is essential for blood production.
Bone marrow transplantation is a treatment in which the patient’s abnormal bone marrow is replaced with healthy cells from the patient’s bone marrow or blood stem cells. This promotes the production of normal blood cells and can treat certain diseases and cancers. Bone marrow transplantation is used to treat some leukemias, lymphomas, and other blood disorders and certain solid tumors and immunodeficiencies, or to reconstruct bone marrow after high-dose chemotherapy or radiation therapy.
Bone Marrow Transplantation Methods:
In this procedure, stem cells from the patient’s own bone marrow or blood are harvested and transplanted back into the patient after chemotherapy or radiation therapy.
In this procedure, bone marrow or blood stem cells from another donor (usually a related family member or a genetic match) are transplanted into the patient. For allogeneic bone marrow transplantation, a compatible donor must be found. The most suitable donor is a family member, especially a sibling, whose genetic characteristics match those of the patient. If there is no matching family donor, a suitable donor can be sought from a database of bone marrow donor registries.